ea0049ep215 | Bone & Osteoporosis | ECE2017
Oprea Theodor-Eugen
, Bonea Mirela
, Florea Suzana
, Barbu Carmen
Osteopetrosis and O.I. are both bone metabolic disorders with opposite features in terms of the metabolic turnover: while osteopetrozis has a low turnover and increased BMD due to the failure of osteoclasts to resorb bone, O.I. is well known as a high turnover disease with low BMD caused bt mutations in the COL1A1 and col COL1A2 genes that encode type 1 procollagen; yet, both condition, in spite of different mechanism, end up with increased ftracure prevalence. We report the c...